Callahan Construction Managers Completes Life Sciences Facility for Revolution Labs in Lexington

Multi-tenant project yields much-needed research space in Lexington

Callahan Construction Managers (Callahan),a full-service construction management company headquartered in Bridgewater, Mass., announced today that it has completed a multi-phase renovation project for Revolution Labs in Lexington. The project features a 180,000 square foot core and shell research building that is occupied by anchor tenants Orum Therapeutics and Alchemab Therapeutics.

The facility was designed from the ground up to support both cutting-edge research and the lifestyle needs of today’s life sciences pioneers. Orum Therapeutics is a private, clinical-stage biotechnology company that is pioneering the development degrader-antibody conjugates (DCAs) for cancer treatment, while Alchemab Therapeutics is developing solutions that utilize the immune system to create novel antibody therapies for challenging diseases.

With a proven track record for overseeing complex, technical, and multi-phase projects, Callahan’s familiarity with working in occupied spaces as well as the unique challenges of the life sciences environment proved impactful while working for Revolution Labs. The team was chosen to first oversee the core and shell of the facility, and then later retained to manage the fit-out of the interior office and lab spaces. The occupied nature of the building during the second phase posed challenges that included lining the pipes of the structure’s sanitary system while the building was in use, requiring restricted water use and proactive planning with laboratory tenants.

In addition, the ongoing supply chain concerns made procurement of advanced laboratory components challenging, including specialty HVAC and electrical equipment. Callahan utilized the pre-construction phase to build a schedule that met critical deadlines while also taking into account what equipment needed to be ordered first to ensure occupancy goals were not impacted by unpredictable delivery dates. Fortunately, strong relationships with suppliers and subcontractors ensured Revolution Labs maintained its preferred timeline.

With the health and safety of occupants a priority, Revolution Labs is on track to achieve WELL Certification. For Callahan, knowing it has helped build a facility that promotes both cutting-edge research and the health of its occupants makes the successful completion a source of pride for all involved.


“We are thrilled to see this new research facility come to life to support the groundbreaking efforts of the researchers that work here,” said Steve Callahan, Jr., vice president – business development, Callahan. “This project showcases the benefit of robust pre-construction planning, along with having a team that understands the specialized nature of lab construction. We wish Revolution Labs well as they utilize this space to its maximum potential.”

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About Callahan Construction Managers
Callahan Construction Managers is a full-service construction management company based in Bridgewater, Mass., with a regional office in White Plains, NY.  Callahan has served the New England and Northeast regions for over 70 years. As one of the region’s largest open shop construction firms, Callahan provides a wide range of preconstruction and construction management services to local, regional, and national clients. Callahan’s markets include multi-family residential, senior housing, affordable housing, hospitality, life sciences, corporate office, educational, retail and tenant fit up. Callahan was voted a 2022 “Top Place to Work” by the Boston Globe and 2021 “Best Place to Work” by the Boston Business Journal. Visit www.callahan-inc.com for more information.


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